BioQuant, the Center for “Quantitative Analysis of Molecular and Cellular Biosystems” at Heidelberg University was established in 2007 as an interdisciplinary University research center that is solely dedicated to research and training in systems biology. BioQuants’s objective is to function as a platform for the development and constant refinement of mathematical models of complex biological systems as well as the swift validation of scientific hypotheses via experimental data. Currently, up to 40 University and non-University research groups (DKFZ, EMBL, the European Media Lab, and the MPI for Medical Research) are affiliated with BioQuant. These research groups are instrumental in implementing numerous national and international systems biology funding initiatives. They include the FORSYS-ViroQuant, HepatoSys, SysMo, and several MedSys, SysTec, and GerontoSys networks, the public-private-partnership program BioMS as well as the Helmholtz Initiative for Systems Biology (SBCancer), and the Excellence Cluster CellNetworks, to some extent.